MARC Record

Leader
001 003534513
003 BE-GnUNI
005 20250201132132.0
008 051103s2007 fluaf ||b |001 ||eng||
010
  
  
a| 2005056902
015
  
  
a| GBA614519 2| bnb
016
7
  
a| 013380737 2| Uk
020
  
  
a| 1584886420
020
  
  
a| 9781584886426
035
  
  
a| (OCoLC)ocm62325140
040
  
  
a| Howest
042
  
  
a| pcc
050
0
0
a| QH324.2 b| .A46 2007
082
0
0
a| 570.285 2| 22
084
  
  
a| 570 2| vsiso
100
1
  
a| Alon, Uri, d| ....- 0| (viaf)
245
1
3
a| An introduction to systems biology : b| design principles of biological circuits / c| Uri Alon.
260
  
  
a| Boca Raton (Fla.) : b| Chapman & Hall/CRC, c| 2007.
300
  
  
a| XVI, 301 p.: ill.
490
0
  
a| Chapman and Hall/CRC mathematical and computational biology series
504
  
  
a| Includes bibliographical references (p. 271-293) and index.
520
  
  
a| An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models. Explains the basic circuitry in transcription regulation, signal transduction, and developmental networks Includes examples ranging from bacterial chemotaxis through developmental patterning and neuronal circuits to immune recognition Examines the principle of robustness Details how constrained evolutionary optimization can be used to understand optimal circuit design Considers how kinetic proofreading and other mechanisms can minimize errors made in biological information-processing Includes solved problems after each chapter that detail topics not discussed in the main text Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The text avoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles.
650
  
7
a| Basic Sciences. Biology x| Biosystematics. 2| z
650
  
7
a| Biological systems x| Mathematical models. 2| lcsh
650
  
7
a| Computational biology. 2| lcsh
650
  
7
a| Systems biology. 2| lcsh
856
4
  
u| http://www.loc.gov/catdir/enhancements/fy0654/2005056902-d.html 3| Publisher description
852
4
  
b| HWSJS c| SJS j| SJS.BOEK.570.INTR.2007 p| 1005506
920
  
  
a| book